Specification
| Description | Recombinant protein from the full-length sequence of homo sapiens peripherin 2 (PRPH2) (NM_000322). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | P23942 |
| Entry Name | PRPH2_HUMAN |
| Gene Names | PRPH2 PRPH RDS TSPAN22 |
| Alternative Gene Names | PRPH RDS TSPAN22 |
| Alternative Protein Names | Peripherin-2 (Retinal degeneration slow protein) (Tetraspanin-22) (Tspan-22) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 346 |
| Molecular Weight(Da) | 39186 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MALLKVKFDQKKRVKLAQGLWLMNWFSVLAGIIIFSLGLFLKIELRKRSDVMNNSESHFVPNSLIGMGVLSCVFNSLAGKICYDALDPAKYARWKPWLKPYLAICVLFNIILFLVALCCFLLRGSLENTLGQGLKNGMKYYRDTDTPGRCFMKKTIDMLQIEFKCCGNNGFRDWFEIQWISNRYLDFSSKEVKDRIKSNVDGRYLVDGVPFSCCNPSSPRPCIQYQITNNSAHYSYDHQTEELNLWVRGCRAALLSYYSSLMNSMGVVTLLIWLFEVTITIGLRYLQTSLDGVSNPEESESESEGWLLEKSVPETWKAFLESVKKLGKGNQVEAEGAGAGQAPEAG |
Background
| Function | FUNCTION: Essential for retina photoreceptor outer segment disk morphogenesis, may also play a role with ROM1 in the maintenance of outer segment disk structure (By similarity). Required for the maintenance of retinal outer nuclear layer thickness (By similarity). Required for the correct development and organization of the photoreceptor inner segment (By similarity). {ECO:0000250|UniProtKB:P15499}. |
| Pathway | |
| Protein Families | PRPH2/ROM1 family |
| Tissue Specificity | Retina (photoreceptor). In rim region of ROS (rod outer segment) disks. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |